On 22 January 1517, Ottoman forces, under the command of Sultan Selim I, decisively captured Cairo, the illustrious capital of the Mamluk Sultanate.
This victory marked the culmination of the Ottoman-Mamluk War, resulting in the absorption of Egypt into the rapidly expanding Ottoman Empire.
The fall of Cairo not only signified the end of the Mamluk reign but also established the Ottomans as the dominant power in the Islamic world, controlling key trade routes and the revered cities of Mecca and Medina.